49ers vs Cardinals

Head-to-Head Record

All Time
ARI
Cardinals 22 Wins
0 Ties
SF
49ers 27 Wins

Average Scores

49ers vs Cardinals (All Time)

Cardinals 20.9 PPG
49ers 23.6 PPG

Home Field Advantage

49ers vs Cardinals (All Time)

Cardinals at Home 12-12
50% Win Rate
49ers at Home 15-10
60% Win Rate

Highest Scoring Game

49ers vs Cardinals

74 Total Points
Dec 17, 2023
Cardinals 29 - 45 49ers

Last Meeting

49ers vs Cardinals

Nov 16, 2025
49ers 41 - 22 Cardinals
49ers Won

Rivalry Facts

These teams have played 49 times, first meeting in 1999.

The 49ers lead the all-time series 22-27.

The home team has won 55% of games in this matchup.

The last time 49ers won at Cardinals was Dec 17, 2023.

Largest victory: 40 points (Cardinals on Sep 27, 2015)

Current Form (Last 10)

ARI
Cardinals
1-9 L9
Recent: L L L L L L L W L L ← Latest
SF
49ers
6-3 W6
Recent: W W W W L W L W L ← Latest

49ers are the hotter team coming into this matchup.

Recent Meetings (Last 5)

Nov 16, 2025
SF W
Cardinals 22
@
49ers 41
Sep 21, 2025
SF W
Cardinals 15
@
49ers 16
Jan 05, 2025
ARI W
Cardinals 47
@
49ers 24
Oct 06, 2024
ARI W
Cardinals 24
@
49ers 23
Dec 17, 2023
SF W
Cardinals 29
@
49ers 45

Upcoming Games for Cardinals

Dec 28, 2025
@ Bengals
Paycor Stadium, Cincinnati, OH
get tickets
Jan 04, 2026
@ Rams
SoFi Stadium, Inglewood, CA
get tickets
View Cardinals Team Page

Upcoming Games for 49ers

Dec 29, 2025
vs Bears
Levi's Stadium, Santa Clara, CA
get tickets
Jan 04, 2026
vs Seahawks
Levi's Stadium, Santa Clara, CA
get tickets
View 49ers Team Page

Historical Performance (All-Time Stats)

ARI

Cardinals

All-time performance
ALL-TIME WIN % 105 Seasons
41%
593-812-41
PLAYOFF SEASONS 105 total
12
11% of seasons
CHAMPIONSHIPS Last: 1947
2
1925, 1947
RECENT FORM Last 5 years
42%
35-49-0
SF

49ers

All-time performance
ALL-TIME WIN % 79 Seasons
54%
630-526-16
PLAYOFF SEASONS 79 total
30
38% of seasons
CHAMPIONSHIPS Last: 1994
5
1981, 1984, 1988, 1989, 1994
RECENT FORM Last 5 years
56%
47-37-0

Top Seasons by Wins

All-Time Records
ARI
Cardinals
Top 5 seasons
 Team page →
#1
2015
Lost Conference Championship
13-3-0
81.3%
#2
1925
Won Conference Championship
11-2-1
78.6%
#3
1948
Lost Conference Championship
11-1-0
91.7%
#4
1975
Lost Divisional Round
11-3-0
78.6%
#5
2014
Lost Wild Card Round
11-5-0
68.8%
SF
49ers
Top 5 seasons
 Team page →
#1
1984
Won Super Bowl
15-1-0
93.8%
#2
1989
Won Super Bowl
14-2-0
87.5%
#3
1990
Lost Conference Championship
14-2-0
87.5%
#4
1992
Lost Conference Championship
14-2-0
87.5%
#5
1981
Won Super Bowl
13-3-0
81.3%

Related Matchups

Other Cardinals Matchups
ARI
Cardinals
vs
NYJ
Jets
View Matchup
Other Cardinals Matchups
ARI
Cardinals
vs
NYG
Giants
View Matchup
Other Cardinals Matchups
ARI
Cardinals
vs
LV
Raiders
View Matchup